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NAD+
$249.00
NAD (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell of your body, playing a key role in energy production, metabolism, and cellular repair. Our NAD+ 1000mg is designed to enhance cognitive function, support energy metabolism, and combat the effects of aging. Ideal for individuals seeking a natural way to boost energy, improve focus, and promote overall vitality, this high-potency formula helps replenish NAD levels to optimize your body’s performance.
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$249.00
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Research
NAD+ (Nicotinamide Adenine Dinucleotide): Cellular Bioenergetics and Molecular Function
Molecular Overview
NAD+ is a pyridine nucleotide coenzyme ubiquitously present in all cells, playing a critical role in cellular energy production, metabolic regulation, and enzymatic signaling.
It functions as a redox cofactor in key metabolic pathways including glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation, facilitating ATP synthesis.
NAD+ also serves as a substrate for sirtuins, poly(ADP-ribose) polymerases (PARPs), and ADP-ribosyltransferases, modulating DNA repair, genomic stability, mitochondrial function, and cellular stress responses.
Endogenous NAD+ levels decline with age, contributing to fatigue, cognitive decline, metabolic dysregulation, and accelerated cellular aging.
Mechanism of Action
1. Energy Metabolism
- Functions as an electron carrier in mitochondrial respiration, supporting efficient ATP generation.
- Enhances cellular bioenergetics, sustaining physical and cognitive performance.
2. Neurocognitive and Cognitive Enhancement
- Supports neuronal energy metabolism, improving mental clarity, focus, and memory retention.
- Reduces oxidative stress in neural tissue, enhancing cognitive resilience and mental stamina.
3. Cellular Repair and Longevity
- Activates sirtuin-mediated pathways, promoting DNA repair, antioxidant defenses, and mitochondrial biogenesis.
- Facilitates genomic maintenance and cellular rejuvenation, counteracting age-associated decline.
4. Recovery and Systemic Support
- Supports detoxification and metabolic homeostasis through NAD+-dependent enzymatic reactions.
- Accelerates recovery from physical stress, exercise, or illness, promoting overall physiological resilience.
Physiological and Clinical Benefits
- Boosts Cognitive Function: Enhances focus, attention, memory, and mental clarity.
- Enhances Energy Metabolism: Optimizes mitochondrial ATP production for sustained vitality.
- Anti-Aging Support: Reduces oxidative stress and promotes long-term cellular health.
- Improves Cellular Repair: Facilitates DNA repair, mitochondrial function, and overall tissue rejuvenation.
- Supports Recovery and Wellness: Accelerates restoration after stress, illness, or metabolic challenge.
Therapeutic and Research Applications
NAD+ supplementation or intravenous administration is commonly applied to:
- Promote healthy aging and longevity
- Support cognitive performance and neuroprotection
- Enhance energy metabolism and physical stamina
- Facilitate detoxification and cellular repair
- Improve overall wellness and recovery efficiency
NAD+ represents a fundamental coenzyme for cellular bioenergetics, neuroprotection, and longevity, integrating energy production, DNA repair, and anti-aging mechanisms into a holistic support framework for optimal human performance.
Legal Policy:
This product is strictly for research purposes only and is intended solely for in vitro testing and laboratory experimentation. The information provided on this website is for educational use and does not permit the introduction of this product into humans or animals. Handling of this product is restricted to licensed and qualified professionals. It is not classified as a drug, food, or cosmetic, and should not be misrepresented or used as such.
Disclaimer
All products sold on this site are for research and development use only. They are not intended for human or animal use.
The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.
Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.
Ingredients
Molecular Formula:
FAQ
1. What is NAD+, and why does it matter?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell, essential for energy production, cellular repair, and brain function. As we age, NAD+ levels decline, which can lead to fatigue, brain fog, and signs of aging. Supplementing with NAD+ helps restore these levels, supporting energy, clarity, and longevity.
2. What are the benefits of NAD+ injections?
NAD+ injections deliver fast, effective absorption directly into the bloodstream. Users often report:
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Increased energy
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Improved focus and memory
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Better mood and mental clarity
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Faster recovery from stress, workouts, or illness
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Anti-aging and detox support
It’s a popular option for those looking to boost overall wellness and performance.
3. What is NAD+ used for?
NAD+ is commonly used to:
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Promote healthy aging
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Enhance mental performance
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Increase energy and stamina
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Support detox and recovery
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Optimize overall wellness
White Papers
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.
Rajman L, Chwalek K, Sinclair DA.
Cell Metab. 2018 Mar 6;27(3):529-547. doi: 10.1016/j.cmet.2018.02.011.
PMID: 29514064
NAD+ homeostasis in human health and disease.
Zapata-Pérez R, Wanders RJA, van Karnebeek CDM, Houtkooper RH.
EMBO Mol Med. 2021 Jul 7;13(7):e13943. doi: 10.15252/emmm.202113943. Epub 2021 May 27.
PMID: 34041853
NAD metabolism: Role in senescence regulation and aging.
Chini CCS, Cordeiro HS, Tran NLK, Chini EN.
Aging Cell. 2024 Jan;23(1):e13920. doi: 10.1111/acel.13920. Epub 2023 Jul 9.
PMID: 37424179
NAD+ Metabolism in Cardiac Health, Aging, and Disease.
Abdellatif M, Sedej S, Kroemer G.
Circulation. 2021 Nov 30;144(22):1795-1817. doi: 10.1161/CIRCULATIONAHA.121.056589. Epub 2021 Nov 29.
PMID: 34843394
NAD+-Consuming Enzymes in Stem Cell Homeostasis.
Ji X, Zheng M, Yu T, Kang J, Fan T, Xu B.
Oxid Med Cell Longev. 2023 Feb 8;2023:4985726. doi: 10.1155/2023/4985726. eCollection 2023.
PMID: 36819783
NAD+ Precursors in Human Health and Disease: Current Status and Future Prospects.
Yaku K, Nakagawa T.
Antioxid Redox Signal. 2023 Dec;39(16-18):1133-1149. doi: 10.1089/ars.2023.0354. Epub 2023 Aug 4.
PMID: 37335049
NAD+-Increasing Strategies to Improve Cardiometabolic Health?
Blanco-Vaca F, Rotllan N, Canyelles M, Mauricio D, Escolà-Gil JC, Julve J.
Front Endocrinol (Lausanne). 2022 Jan 31;12:815565. doi: 10.3389/fendo.2021.815565. eCollection 2021.
PMID: 35173682
Host NAD+ metabolism and infections: therapeutic implications.
Singhal A, Cheng CY.
Int Immunol. 2019 Feb 15;31(2):59-67. doi: 10.1093/intimm/dxy068.
PMID: 30329059
Spatiotemporal monitoring of NAD+ metabolism with fluorescent biosensors.
Chen W, Liu S, Yang Y, Zhang Z, Zhao Y.
Mech Ageing Dev. 2022 Jun;204:111657. doi: 10.1016/j.mad.2022.111657. Epub 2022 Mar 12.
PMID: 35288098
NAD Analogs in Aid of Chemical Biology and Medicinal Chemistry.
Depaix A, Kowalska J.
Molecules. 2019 Nov 19;24(22):4187. doi: 10.3390/molecules24224187.
PMID: 31752261





































