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Ipamorelin + CJC 1295 Blend

Name: Ipamorelin + CJC 1295 Blend
Brand: Tides Peptides

Price

$179.00

The Ipamorelin + CJC-1295 (No DAC) Blend is a synergistic peptide combination designed to naturally boost growth hormone levels without overstimulation or unwanted side effects. Together, these peptides work to enhance recovery, support lean muscle development, promote fat loss, and slow down signs of aging. This blend is ideal for those looking to optimize performance, body composition, and overall vitality—safely and effectively.

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$179.00

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Research

Ipamorelin + CJC-1295 (No DAC): Molecular Mechanisms and Growth Hormone Modulation

Molecular Overview

The Ipamorelin + CJC-1295 (No DAC) blend is a dual growth hormone-releasing peptide (GHRP) and growth hormone-releasing hormone (GHRH) analog system designed to stimulate endogenous growth hormone (GH) secretion without the negative feedback suppression associated with exogenous GH administration.

Ipamorelin is a selective GHRP that binds to ghrelin/growth hormone secretagogue receptors (GHS-R1a) on pituitary somatotrophs, inducing pulsatile GH release.
CJC-1295 (No DAC) is a GHRH analog that activates GHRH receptors (GHRHR), elevating cAMP-dependent signaling to enhance somatotroph transcriptional activity and GH secretion.

The combination achieves synergistic stimulation of endogenous GH, leading to downstream increases in IGF-1, improved anabolic signaling, and optimized metabolic function.

Mechanism of Action

1. Endogenous Growth Hormone Stimulation

Ipamorelin selectively activates GHS-R1a, increasing pulsatile GH exocytosis.
CJC-1295 (No DAC) engages GHRHR, upregulating adenylyl cyclase → cAMP → PKA → GH gene transcription pathways.
Together, they amplify GH pulse amplitude and frequency, enhancing IGF-1 synthesis in the liver and peripheral tissues.

2. Metabolic Effects

Increases lipolysis and fatty acid oxidation, reducing adipose tissue deposition.
Enhances muscle protein synthesis via mTOR and Akt signaling, supporting lean mass accrual and muscle recovery.
Improves energy utilization and cellular metabolism, contributing to optimized body composition.

3. Recovery and Tissue Regeneration

Stimulates collagen deposition, fibroblast proliferation, and tendon/ligament repair, accelerating post-exercise and injury recovery.
Enhances stem cell activation and tissue regenerative pathways, supporting anti-aging effects.

4. Sleep and Neuroendocrine Support

Pulsatile GH release promotes slow-wave (deep) sleep, improving sleep architecture and restorative recovery.
Supports cognitive clarity and neuroprotection via IGF-1–mediated neurotrophic effects.

Physiological and Clinical Benefits

Enhanced GH and IGF-1 Levels: Promotes natural anabolic and regenerative signaling.
Lean Muscle Development: Supports hypertrophy and strength gains.
Fat Metabolism: Increases lipolysis, reduces visceral and subcutaneous fat.
Recovery Acceleration: Improves post-exercise repair and reduces tissue fatigue.
Sleep Optimization: Enhances deep, restorative sleep essential for recovery and hormone balance.
Anti-Aging Support: Promotes cellular regeneration, skin elasticity, and overall vitality.

Therapeutic and Research Applications

The Ipamorelin + CJC-1295 (No DAC) blend is commonly studied and applied for:

Body composition optimization (fat loss, lean mass gain)
Post-exercise and injury recovery enhancement
Anti-aging and regenerative medicine
Sleep and neuroendocrine support
Safe endogenous GH augmentation without exogenous GH administration

This peptide combination represents a highly targeted, physiologically aligned approach to optimizing endocrine health, tissue repair, metabolism, and longevity.

Legal Policy:

This product is strictly for research purposes only and is intended solely for in vitro testing and laboratory experimentation. The information provided on this website is for educational use and does not permit the introduction of this product into humans or animals. Handling of this product is restricted to licensed and qualified professionals. It is not classified as a drug, food, or cosmetic, and should not be misrepresented or used as such.

Disclaimer

All products sold on this site are for research and development use only. They are not intended for human or animal use.

The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.

Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.

Ingredients

Molecular Formula

Ipamorelin:

CAS Number: 170851-70-4
Molecular Formula: C₃₈H₄₉N₉O₅
Peptide Sequence: X-His-D-2-Nal-D-Phe-Lys-NH₂

CJC-1295 Without DAC:

CAS Number: 446262-90-4
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂
Peptide Sequence: Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Leu-Ser-Arg

View Certificate of Analysis

FAQ

1. What is the Ipamorelin + CJC 1295 Blend (No DAC), and why does it matter?

The peptide blend of Ipamorelin + CJC 1295 Blend (No DAC) naturally stimulate your body’s growth hormone (GH) production. Together, they promote fat loss, lean muscle growth, improved recovery, and better sleep, all without the side effects of synthetic HGH.

2. What are the benefits of this peptide blend?

The Ipamorelin + CJC 1295 Blend is one of the most popular growth hormone-releasing blends because it offers: