GLOW Blend 70mg

Molecular Overview

BPC-157 is a stable 15–amino-acid peptide derived from gastric proteins, known for accelerating soft-tissue repair, angiogenesis, and gastrointestinal protection.

TB-500 (Thymosin Beta-4 fragment) is a synthetic 43-amino-acid peptide that supports cell migration, actin regulation, and wound healing.

GHK-Cu is an endogenous tripeptide–copper complex found in human plasma, known for collagen renewal, anti-inflammatory effects, and skin/hair regeneration.

Together, these peptides promote multi-layer healing: tissue repair, improved circulation, reduced inflammation, and enhanced extracellular matrix remodeling.

Mechanisms of Action

1. Angiogenesis & Growth Factor Modulation

• BPC-157 increases Egr-1 and VEGF, improving vascular repair.

• TB-500 supports endothelial cell migration and blood flow.

• Combined, they accelerate capillary formation and tissue perfusion.

2. Tissue Repair & Cell Migration

• Both stimulate fibroblast growth, tendon/ligament repair, and muscle satellite cell activation.

• TB-500 enhances actin-based cell movement, supporting faster wound closure.

3. Gastrointestinal Protection

• BPC-157 improves epithelial turnover and protects mucosal tissue from chemical or oxidative injury.

4. Anti-Inflammatory Effects

• Downregulates TNF-α and IL-6 while increasing IL-10, reducing local and systemic inflammation.

GHK-Cu Mechanisms

Extracellular Matrix Remodeling

• Stimulates collagen I & III, elastin, and GAG production through TGF-β pathways, improving skin firmness and elasticity.

Cellular Repair

• Enhances fibroblast and keratinocyte activity, VEGF, and NGF expression, aiding wound healing and microcirculation.

Anti-Inflammatory & Antioxidant

• Lowers pro-inflammatory cytokines and boosts antioxidant enzymes such as SOD.

Copper Delivery

• Supplies copper to enzymes essential for collagen cross-linking, antioxidant protection, and pigmentation regulation.

Hair Follicle Stimulation

• Activates Wnt/β-catenin signaling, improving follicle size, density, and anagen phase activation.

Physiological Benefits

BPC-157 + TB-500 may support:

• Faster recovery of muscles, tendons, ligaments

• Enhanced angiogenesis and nutrient delivery

• Reduced inflammation and swelling

• Improved joint comfort and mobility

• GI protection and mucosal healing

• Post-surgical and sports injury recovery

GHK-Cu may support:

• Skin repair, elasticity, and anti-aging

• Hair regrowth and scalp health

• Reduction of oxidative stress and inflammation

• Faster wound healing and scar improvement

• Post-procedure recovery

Therapeutic & Research Applications

BPC-157 + TB-500:

• Sports injuries and chronic overuse

• Muscle and connective-tissue regeneration

• Post-surgical healing

• Joint inflammation support

• Systemic recovery for active individuals

GHK-Cu:

• Dermatology and anti-aging research

• Hair restoration studies

• Tissue engineering applications

• Oxidative stress modulation

• Skin recovery after procedures (microneedling, PRP, lasers)

Legal Policy

This product is for research use only and intended strictly for in vitro laboratory studies. It is not approved for human or animal use. It is not a drug, food, or cosmetic. Handling is restricted to qualified professionals, and no part of this information should be interpreted as medical advice or authorization for clinical application.

All products sold on this site are for research and development use only. They are not intended for human or animal use.
 

The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.

Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.

Molecular Formula

BPC‑157

• Formula: C₆₂H₉₈N₁₆O₂₂
• Molecular Weight: 1,419.5 g/mol
• Amino Acid Sequence: Gly‑Glu‑Pro‑Pro‑Pro‑Gly‑Lys‑Pro‑Ala‑Asp‑Asp‑Ala‑Gly‑Leu‑Val

TB‑500 (Thymosin β4 fragment 17–23)

• Formula (combined): C₈₂H₁₃₃N₂₁O₂₈S
• Approx. Molecular Weight: ~1,894 g/mol
• Amino Acid Sequence: N‑Ac‑Ser‑Asp‑Lys‑Pro‑His‑Gln‑Ala‑Gly

GHK-Cu

• Formula: C₁₄H₂₃CuN₆O₄
• Molecular Weight: ~401.97 g/mol
• Amino Acid Sequence: Gly-His-Lys.Cu.XHAc

1. What is the GLOW peptide blend, and why does it matter?

GLOW is a research-oriented injectable peptide blend that usually combines:

• GHK-Cu – a naturally occurring copper peptide associated with tissue repair, skin health, and anti-inflammatory activity.
• TB-500 – a synthetic fragment of Thymosin Beta-4, researched for cell migration, recovery, and healing.
• BPC-157 – a peptide fragment derived from a gastric protein, studied for gut integrity, tissue repair, and inflammation modulation.
   

Each component has distinct biological pathways related to repair, inflammation control, collagen production, and angiogenesis. When combined, researchers consider GLOW a blend that targets multiple mechanisms of regeneration—cell movement, collagen remodeling, vascular support, and inflammation regulation. This makes GLOW significant in experimental models of recovery, wound healing, and tissue protection.

2. What are the benefits of the GLOW peptide (GHK-Cu + TB-500 + BPC-157) blend?

GHK-Cu

• Enhances collagen synthesis, skin repair, and anti-aging pathways
• Reduces oxidative stress and inflammation
• Supports angiogenesis (blood vessel formation)

TB-500

• Promotes cell migration to injury sites
• Supports tissue repair in muscle, tendon, and ligament models
• Modulates inflammatory responses
• May improve flexibility and reduce stiffness (observed in animal studies)

BPC-157

• Supports gut lining integrity in research
• Studied for connective-tissue repair (tendon, ligament, muscle)
• Demonstrates anti-inflammatory and protective effects
• Investigated for nerve repair and vascular protection

Together, these research peptides may show synergistic effects involving:

• Faster wound healing
• Improved tissue regeneration
• Enhanced collagen remodeling
• Reduced inflammation
• Support for skin, muscle, and connective-tissue recovery
• Increased angiogenesis and improved microcirculation

3. What is GLOW used for in research?

GLOW is primarily used in experimental and laboratory settings. Common areas of interest include:

Research Applications

• Skin regeneration and collagen studies
  (GHK-Cu plays a major role here)
• Muscle, tendon, and ligament healing models
  (TB-500 + BPC-157 contributions)
• Gut barrier integrity and inflammation experiments
  (BPC-157 focus)
• Angiogenesis and microvascular repair studies
• Nerve regeneration investigations
  (primarily BPC-157 interest)
• General wound-healing research, combining:
  • tissue repair
  • anti-inflammatory action
  • improved blood flow
  • cellular migration
  • collagen remodeling

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

This study explores the effects of BPC-157 on tendon fibroblasts, highlighting its potential in musculoskeletal tissue repair.

Gastric Pentadecapeptide Body Protection Compound BPC 157 and Its Role in Accelerating Musculoskeletal Soft Tissue Healing

This article reviews the role of BPC-157 in accelerating the healing of musculoskeletal soft tissues.

Stable Gastric Pentadecapeptide BPC 157 Can Improve the Healing Course of Spinal Cord Injury and Lead to Functional Recovery in Rats

This research examines the potential of BPC-157 in promoting recovery from spinal cord injuries. ​

Thymosin Beta-4: A Promising Peptide for Tissue Repair and Regeneration

This review discusses the regenerative effects of TB-500, focusing on its role in tissue repair and inflammation modulation.

Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.
Pickart L, Margolina A.Int J Mol Sci. 2018 Jul 7;19(7):1987. doi: 10.3390/ijms19071987.PMID: 29986520 Free PMC article. Review.

The potential of GHK as an anti-aging peptide.
Dou Y, Lee A, Zhu L, Morton J, Ladiges W.Aging Pathobiol Ther. 2020 Mar 27;2(1):58-61. doi: 10.31491/apt.2020.03.014.PMID: 35083444 Free PMC article.

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate.
Bossak-Ahmad K, Wiśniewska MD, Bal W, Drew SC, Frączyk T.Int J Mol Sci. 2020 Aug 27;21(17):6190. doi: 10.3390/ijms21176190.PMID: 32867146 Free PMC article.

The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice.
Park JR, Lee H, Kim SI, Yang SR.Oncotarget. 2016 Sep 6;7(36):58405-58417. doi: 10.18632/oncotarget.11168.PMID: 27517151 Free PMC article.

GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration.
Pickart L, Vasquez-Soltero JM, Margolina A.Biomed Res Int. 2015;2015:648108. doi: 10.1155/2015/648108. Epub 2015 Jul 7.PMID: 26236730 Free PMC article. Review.

Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application.
Dymek M, Olechowska K, Hąc-Wydro K, Sikora E.Pharmaceutics. 2023 Oct 18;15(10):2485. doi: 10.3390/pharmaceutics15102485.PMID: 37896245 Free PMC article.

The human tri-peptide GHK and tissue remodeling.
Pickart L.J Biomater Sci Polym Ed. 2008;19(8):969-88. doi: 10.1163/156856208784909435.PMID: 18644225 Review.

Polyaspartic acid, 2-acrylamido-2-Methyl propane sulfonic acid and sodium alginate based biocompatible stimuli responsive polymer gel for controlled release of GHK-Cu peptide for wound healing.
Sharma S, Anwar MF, Dinda AK, Singhal M, Dua A, Malik A.J Biomater Appl. 2022 Jul;37(1):132-150. doi: 10.1177/08853282221076708. Epub 2022 Mar 26.PMID: 35341370

Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?
Ogórek K, Nowak K, Wadych E, Ruzik L, Timerbaev AR, Matczuk M.Molecules. 2025 Jan 1;30(1):136. doi: 10.3390/molecules30010136.PMID: 39795193 Free PMC article. Review