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SS-31 (Elamipretide) is a next-generation, mitochondria-targeting research peptide engineered to support cellular energy, resilience, and metabolic efficiency at the source. By selectively binding to cardiolipin within the inner mitochondrial membrane, SS-31 is studied for its ability to enhance mitochondrial performance, reduce oxidative stress, and preserve cellular function under high-demand conditions. Researchers value SS-31 for its potential to promote sustained energy production, support muscle and tissue performance, and protect cells from age and stress-related decline making it a premium peptide for advanced mitochondrial, longevity, and metabolic research.
Quantity
Research
Molecular Overview
SS-31 is a cell-permeable, mitochondria-specific peptide engineered to bind cardiolipin, a phospholipid critical to mitochondrial membrane integrity. By stabilizing cardiolipin interactions, SS-31 is studied for its ability to enhance electron transport chain efficiency and reduce reactive oxygen species (ROS) generation.
Key research associations include:
· Mitochondrial bioenergetics optimization
· Reduction of oxidative stress markers
· Preservation of mitochondrial membrane integrity
· Support of ATP production pathways
· Cellular resilience under metabolic stress
These properties make SS-31 a valuable compound in mitochondrial and cellular aging research.
Mechanisms of Action
1. Mitochondrial Targeting SS-31 selectively accumulates within the inner mitochondrial membrane, enabling direct interaction with cardiolipin and mitochondrial proteins.
2. Reduction of Oxidative Stress Research models demonstrate SS-31’s ability to limit excess reactive oxygen species, supporting redox balance and cellular stability.
3. Bioenergetic Support By improving electron transport efficiency, SS-31 is associated with enhanced ATP generation and metabolic efficiency in research settings.
Physiological & Performance-Related Research Benefits
· Support of mitochondrial function and efficiency
· Reduction of oxidative stress in cellular models
· Preservation of muscle and tissue energy metabolism
· Enhancement of cellular stress resilience
· Protection of mitochondrial membrane structure
· Support for metabolic and age-related research pathways
Therapeutic Research Applications
· SS-31 is commonly explored in studies involving:
· Mitochondrial dysfunction and bioenergetics
· Aging and longevity research
· Muscle performance and fatigue models
· Cardiovascular and metabolic research
· Oxidative stress and cellular damage studies
· Neurodegenerative and metabolic stress models
· Energy metabolism and ATP regulation research
Disclaimer
All products sold on this site are for research and development use only. They are not intended for human or animal use.
The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.
Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.
Ingredients
Molecular Formula
SS-31
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Molecular Formula: C₂₀H₃₀N₆O₅
· Molecular Sequence: D-Arg-Dmt-Lys-Phe
· Molecular Weight: Approximately 639.8 g/mol
FAQ
1. What is SS-31 and why does it matter?
SS-31 is a synthetic tetrapeptide developed to specifically target mitochondria. Unlike general antioxidants, SS-31 is designed to localize within the mitochondrial membrane, allowing it to directly influence mitochondrial efficiency and oxidative balance. This targeted activity has made it a significant focus in cellular aging and metabolic research.
2. What are the research benefits of SS-31?
Research studies suggest SS-31 may:
· Support mitochondrial energy production
· Reduce oxidative stress at the cellular level
· Preserve mitochondrial membrane integrity
· Enhance cellular resilience under stress
· Support muscle and metabolic function in models
· Demonstrate favorable stability and low toxicity in research settings
3. What is SS-31 used for in research?
SS-31 is primarily used in laboratory and preclinical research exploring:
· Mitochondrial health and dysfunction
· Aging and longevity mechanisms
· Muscle physiology and endurance models
· Metabolic and cardiovascular stress pathways
· Oxidative damage and cellular repair processes
Due to its mitochondria-specific activity, SS-31 continues to be a cornerstone peptide in advanced bioenergetic and cellular research.
