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TB-500
$150.00
TB-500 (Thymosin Beta-4 peptide fragment) is a 43-amino-acid peptide widely recognized for its role in supporting tissue flexibility, mobility, and the body’s natural recovery processes. TB-500 is a versatile research peptide valued for its ability to support healing, flexibility, mobility, and tissue resilience through its unique action on actin dynamics, angiogenesis, and cellular repair pathways. Ideal for athletes or anyone seeking to optimize recovery and physical performance, TB-500 offers a targeted and effective approach to supporting the body’s natural restoration processes. Known for its influence on the actin cytoskeleton, a major component of cellular structure, B-500 helps facilitate efficient cell migration, angiogenesis, and tissue remodeling, making it a popular choice among athletes, active individuals, and those seeking to enhance physical resilience. By promoting healthy cellular movement and supporting balanced inflammatory responses, research shows TB-500 is often used to help reduce stiffness and encourage smoother, more comfortable motion. Its supportive role in circulation and nutrient delivery further contributes to an environment that favors overall healing, improved mobility, and enhanced flexibility.
Quantity
Research
Molecular Overview
TB-500 is a synthetic version of a naturally occurring peptide associated with the protein Thymosin Beta-4 (Tβ4). This peptide plays a key role in:
- Actin regulation – helping maintain structural integrity and cellular movement
- Angiogenesis – supporting the development of new blood vessels
- Cellular migration and tissue repair
- Inflammatory modulation
Through these functions, TB-500 aids in orchestrating multi-level tissue support and recovery, from structural remodeling to improved nutrient flow.
Mechanisms of Action
1. Angiogenesis & Circulatory Support
TB-500 encourages endothelial cell movement and organization; processes associated with the formation of new capillaries. This may help improve oxygenation and nutrient delivery in areas under physical stress.
2. Tissue Repair & Cell Migration
TB-500’s influence on the actin cytoskeleton plays a critical role in cell mobility. By supporting fibroblast and satellite cell activity, TB-500 promotes efficient tissue remodeling—especially in muscle, tendon, ligament, and connective tissue.
3. Balanced Inflammatory Response
Research indicates TB-500 may help modulate key cytokines involved in inflammation, supporting comfort, faster recovery from strain, and overall tissue resilience.
Physiological & Performance-Related Benefits (Non-Medical)
- Support for tendon, ligament, muscle, and soft tissue recovery
- Enhanced flexibility, mobility, and range of motion
- Reduced general inflammation-related stiffness
- Improved cellular repair and tissue remodeling
- Support for circulation and angiogenesis
- Overall physical resilience and recovery efficiency
TB-500 is frequently explored for its role in:
- Sports-related stress and physical exertion
- Tissue remodeling and performance optimization
- Soft tissue and musculoskeletal support
- Angiogenesis and cellular repair pathways
- Recovery enhancement in active individuals
Legal Policy:
This product is strictly for research purposes only and is intended solely for in vitro testing and laboratory experimentation. The information provided on this website is for educational use and does not permit the introduction of this product into humans or animals. Handling of this product is restricted to licensed and qualified professionals.
It is not classified as a drug, food, or cosmetic, and should not be misrepresented or used as such.
Disclaimer
All products sold on this site are for research and development use only. They are not intended for human or animal use.
The statements on this website have not been evaluated by the US Food and Drug Administration (FDA). Our products and content are not intended to diagnose, treat, cure, or prevent any disease.
Tides Peptides is a chemical supplier, not a compounding pharmacy or a chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act.
Ingredients
Molecular Formula
TB-500 (Thymosin β4 fragment 17–23)·
- Amino Acid Sequence: N-Ac-Ser-Asp-Lys-Pro-His-Gln-Ala-Gly·
- Formula (combined): C₈₂H₁₃₃N₂₁O₂₈S·
- Approx. Molecular Weight: ~1,894 g/mol
FAQ
1. What is the TB-500 Blend, and why does it matter?
TB-500 is a synthetic research peptide designed to mimic a portion of a natural protein called Thymosin Beta-4 (Tβ4), which is found in almost all human and animal cells. This natural protein plays a role in:
- tissue repair
- cell migration
- inflammation modulation
- blood vessel formation
A TB-500 blend typically refers to TB-500 combined with other peptides (often TB-4 fragments or regenerative peptides) used in research settings. Blending is often done to enhance or complement the biological activity of TB-500 for laboratory or experimental purposes. Researchers value TB-500 because it interacts with actin, a protein critical for cell movement and tissue repair. This makes it of interest in studies related to regeneration, healing, inflammation, and cardiovascular biology.
2. What are the benefits of the TB-500 peptide?
Potential research benefits include:
- Enhanced tissue repair Observed in animal studies involving muscle, tendon, skin, and ligament injury.
- Improved cell migration Helps cells move to injury sites more effectively.
- Anti-inflammatory effects May help regulate inflammatory responses in tissue damage.
- Angiogenesis (new blood vessel formation) Useful in research on wound healing and cardiovascular repair.
- Increased flexibility and reduced stiffness Reported anecdotally in certain studies and experimental settings.
3. What is TB-500 used for?
Common research applications:
- Muscle and tendon injury models To study healing rates, tissue regeneration, and recovery.
- Cardiac tissue studies Exploring the potential for improved heart tissue repair after damage.
- Inflammation and immune regulation Used to analyze how Thymosin Beta-4–related peptides influence inflammation.
- Wound-healing experiments Studied for accelerated healing in skin and internal tissues.
- Veterinary or equine performance research Sometimes used experimentally in horses to investigate healing and performance recovery.
White Papers
- Lu Z, Liu Q, Fan Y, Xiao Q, Yin D, Li Y.
- J Am Heart Assoc. 2025 Feb 14;14(4):e038177. doi: 10.1161/JAHA.124.038177.
- PMCID: PMC12074714
Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals.
- Maar K, Thatcher JE, Karpov E, Rendeki S, Gallyas F Jr, Bock-Marquette I.
- Int J Mol Sci. 2025 Apr 26;26(9):4131. doi: 10.3390/ijms26094131.
- PMCID: PMC12072014
- Yang H, Cui GB, Jiao XY, Wang J, Ju G, You SW.
- Cell Mol Neurobiol. 2009 Aug 18;30(1):149-60. doi: 10.1007/s10571-009-9439-6.
- PMCID: PMC11498471
[Research advances on thymosin β4 in promoting wound healing].
- Gao YX, Wang LF, Ba SJ, Cao JL, Li F, Li B, Zhou B.
- Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2022 Apr 20;38(4):378-384. [Article in Chinese] doi: 10.3760/cma.j.cn501120-20210221-00059.
- PMCID: PMC11704510
- Wang Y, Banga L, Ebrahim AS, Carion TW, Sosne G, Berger EA.
- Front Immunol. 2024 Sep 24;15:1458684. doi: 10.3389/fimmu.2024.1458684.
- PMCID: PMC11458456
